Synthetic Studies in Carbohydrate Molecular Diversity:
Development of Antiparasitic Agents
This PhD Thesis of Dr RC Mishra is divided into 5 chapters Chapter 1 This Chapter is a review of the current status of malaria and strategies for its control. Malaria: Current Status and Future Strategies (.pdf File) Chapter 2 This Chapter deals with the synthesis & Biological evaluation of Sugar derived beta amino hydroxamic acids as Antimalarial Agents. Synthesis of Glycosyl b-Amino Hydroxamates as New Antimalarials Chapters 3 has been divided into A and B sub chapters Chapter 3A First sub chapter ie Chapter 3A deals with the Solid Phase Synthesis of a Combinatorial Library of Glycopeptoids Solid Phase Synthesis of a Combinatorial Library of Glycopeptoids Chapter 3B The 2nd Part of Chapter 3 presents soild phase synthesis of dihydropyrimidinone C-Nucleoside synthesis and their evaluation as potentail antifilarial compunds. Chapters 4 has been divided into A and B sub chapters Chapter 4A Chapter 4 A presents the synthesis of aza uracil and thiamidine nucleoside & their DNA topoisomerase-II inhibitory activity. Synthesis and DNA Topoisomerase-II Inhibitory Activity of Unnatural Nucleosides
Chapter 4B In this sub chapter design & synthesis of Dihydrouracil C-Nucleosides has been described. Synthesis of dihydro uracil C-Nucleosides Chapter 5 The last chapter of the thesis of Dr Ram Chandra Mishra presents the design & synthesis of glycosyl oxazolines and their antimalarial activity. Synthesis and antimalarial activity of glycosyl isoxazolines |